Optimising cost-effectiveness of pandemic response under partial intervention measures

  title={Optimising cost-effectiveness of pandemic response under partial intervention measures},
  author={Quang Dang Nguyen and Mikhail Prokopenko},
The COVID-19 pandemic created enormous public health and socioeconomic challenges. The health effects of vaccination and non-pharmaceutical interventions (NPIs) were often contrasted with significant social and economic costs. We describe a general framework aimed to derive adaptive costeffective interventions, adequate for both recent and emerging pandemic threats. We also quantify the net health benefits and propose a reinforcement learning approach to optimise adaptive NPIs. The approach… 


Integrated Quantification of the Health and Economic Impacts of Differing Strategies to Control the COVID-19 Pandemic
This modelling analysis suggests that elimination or suppression is optimal across the usual range of WTP from a health system perspective in high-income countries (HICs) but from a societal perspective, mitigation is favoured unless a HALY is valued at over US$240,000.
COVID-19: The need for an Australian economic pandemic response plan
Developing a sustainable exit strategy for COVID-19: health, economic and public policy implications
exit strategies must capitalise upon periods of relative suppression of COVID-19 to ensure that those affected are identified and receive care, with prioritisation given to those with highest clinical need.
Identifying cost‐effective dynamic policies to control epidemics
It is demonstrated that dynamic policies can produce higher net health benefit than more commonly described static policies that specify a pre‐determined sequence of interventions to employ throughout epidemics.
The Sooner, the Better: The Early Economic Impact of Non-Pharmaceutical Interventions During the COVID-19 Pandemic
The size of the economic shocks triggered by the COVID-19 pandemic and the effects of the associated non-pharmaceutical interventions have not been fully assessed, because the official economic
Modelling transmission and control of the COVID-19 pandemic in Australia
There is a continuing debate on relative benefits of various mitigation and suppression strategies aimed to control the spread of COVID-19. Here we report the results of agent-based modelling using a
How will mass-vaccination change COVID-19 lockdown requirements in Australia?
Mitigating the SARS-CoV-2 Delta disease burden in Australia by non-pharmaceutical interventions and vaccinating children: a modelling analysis
Delta variant outbreaks may be managed by vaccine coverage rates higher than 80% and activation of moderate NPI measures, preventing healthcare facilities from being overwhelmed and suppressing future COVID-19 Delta-like transmission.
Interfering with influenza: nonlinear coupling of reactive and static mitigation strategies
The results show that combining strategies can produce either mutual improvement of performance or interference that reduces the effectiveness of each strategy when they are used together, and that these coupling effects between intervention strategies are extremely sensitive to delay times, compliance rates and the type of contact targeting used to administer prophylaxis.