Optimised PDMS Tunnel Devices on MEAs Increase the Probability of Detecting Electrical Activity from Human Stem Cell-Derived Neuronal Networks

Abstract

Measurement of the activity of human pluripotent stem cell (hPSC)-derived neuronal networks with microelectrode arrays (MEAs) plays an important role in functional in vitro brain modelling and in neurotoxicological screening. The previously reported hPSC-derived neuronal networks do not, however, exhibit repeatable, stable functional network characteristics… (More)
DOI: 10.3389/fnins.2017.00606

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@inproceedings{Toivanen2017OptimisedPT, title={Optimised PDMS Tunnel Devices on MEAs Increase the Probability of Detecting Electrical Activity from Human Stem Cell-Derived Neuronal Networks}, author={Maria Toivanen and Anssi Pelkonen and Meeri E-L M{\"a}kinen and Laura Yl{\"a}-Outinen and Lassi Sukki and Pasi Kallio and Mervi Ristola and Susanna Narkilahti}, booktitle={Front. Neurosci.}, year={2017} }