Optimisation of the extraction of olive (Olea europaea) leaf phenolics using water/ethanol-based solvent systems and response surface methodology.

@article{Mylonaki2008OptimisationOT,
  title={Optimisation of the extraction of olive (Olea europaea) leaf phenolics using water/ethanol-based solvent systems and response surface methodology.},
  author={Stefania Mylonaki and Elias Kiassos and Dimitris P Makris and Panagiotis I. Kefalas},
  journal={Analytical and bioanalytical chemistry},
  year={2008},
  volume={392 5},
  pages={977-85}
}
An experimental setup based on a 2(3) full-factorial, central-composite design was implemented with the aim of optimising the recovery of polyphenols from olive leaves by employing reusable and nontoxic solutions composed of water/ethanol/citric acid as extracting media. The factors considered were (i) the pH of the medium, (ii) the extraction time and (iii… CONTINUE READING