Optimal viral strategies for bypassing RNA silencing

@article{Rodrigo2010OptimalVS,
  title={Optimal viral strategies for bypassing RNA silencing},
  author={Guillermo Rodrigo and Javier Carrera and Alfonso Jaramillo and Santiago F. Elena},
  journal={Journal of The Royal Society Interface},
  year={2010},
  volume={8},
  pages={257 - 268}
}
  • Guillermo Rodrigo, Javier Carrera, +1 author Santiago F. Elena
  • Published in
    Journal of The Royal Society…
    2010
  • Medicine, Biology
  • The RNA silencing pathway constitutes a defence mechanism highly conserved in eukaryotes, especially in plants, where the underlying working principle relies on the repressive action triggered by the intracellular presence of double-stranded RNAs. This immune system performs a post-transcriptional suppression of aberrant mRNAs or viral RNAs by small interfering RNAs (siRNAs) that are directed towards their target in a sequence-specific manner. However, viruses have evolved strategies to escape… CONTINUE READING

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