Optimal treatment strategies for hemophilia: achievements and limitations of current prophylactic regimens.


Prophylactic application of clotting factor concentrates is the basis of modern treatment of severe hemophilia A. In children, the early start of prophylaxis as primary or secondary prophylaxis has become the gold standard in most countries with adequate resources. In adults, prophylaxis is reasonably continued when started as primary or secondary… (More)
DOI: 10.1182/blood-2015-01-528414


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