Optimal timing of saliva collection to detect pepsin in patients with laryngopharyngeal reflux.


OBJECTIVES/HYPOTHESIS To determine salivary pepsin levels as a function of collection time. STUDY DESIGN A prospective, case-control study. METHODS We selected 57 patients with clinical symptoms and signs of laryngopharyngeal reflux who underwent 24-hour multichannel intraluminal impedance-pH (24h MII-pH) monitoring tests, and 12 control subjects… (More)
DOI: 10.1002/lary.26018

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