Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials
@article{Jobs2017OptimalTO, title={Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials}, author={Alexander Jobs and Shamir R. Mehta and Gilles Montalescot and Eric Vicaut and Arnoud WJ van’t Hof and Erik A Badings and Franz-Josef Neumann and Adnan Kastrati and Alessandro Sciahbasi and Paul-Georges Reuter and Fr{\'e}d{\'e}ric Lapostolle and Aleksandra Milo{\vs}evi{\'c} and Goran Stankovi{\'c} and Dejan Milasinovic and Reinhard Vonthein and Steffen Desch and Holger Thiele}, journal={The Lancet}, year={2017}, volume={390}, pages={737-746} }
118 Citations
Timing of percutaneous coronary intervention in non-ST elevation acute coronary syndrome - Meta-analysis and systematic review of literature.
- MedicineCardiovascular revascularization medicine : including molecular interventions
- 2019
Immediate/Early vs. Delayed Invasive Strategy for Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: A Systematic Review and Meta-Analysis
- MedicineFront. Physiol.
- 2017
Early invasive strategy may lead to a lower mortality rate and reduce the risk of refractory ischemia, while immediate invasive therapy shows a benefit in reducing the riskof major bleeding.
An immediate or early invasive strategy in non-ST-elevation acute coronary syndrome: the OPTIMA-2 randomized controlled trial.
- MedicineAmerican heart journal
- 2021
Early invasive strategy for non-ST elevation acute coronary syndrome: a meta-analysis of randomized, controlled trials
- MedicineThe Journal of international medical research
- 2020
This meta-analysis shows that an early angiographic strategy does not improve clinical outcome in patients with NSTE-ACS, and an early invasive strategy might reduce the rate of composite death or re-MI in high-risk patients with GRACE risk scores >140 or elevated cardiac markers.
Very early invasive angiography versus standard of care in higher-risk non-ST elevation myocardial infarction: study protocol for the prospective multicentre randomised controlled RAPID N-STEMI trial
- MedicineBMJ Open
- 2022
The RAPID N- STEMI trial aims to determine whether very early percutaneous revascularisation improves clinical outcomes as compared with a standard of care strategy in higher-risk N-STEMI patients.
The Effect of the Timing of Invasive Management on Cardiac Function in Patients with NSTE-ACS, Insights from the OPTIMA-2 Randomized Controlled Trial
- MedicineJournal of clinical medicine
- 2021
An immediate invasive strategy in NSTE-ACS patients did not result in an improved left ventricular EF or GLS recovery compared with an early strategy, and there was a similar but significant improvement in both EF and GLS in both separate study groups.
Use, timing and outcome of coronary angiography in patients with high-risk non-ST-segment elevation acute coronary syndrome in daily clinical practice: insights from a ‘real world’ prospective registry
- Medicine, PsychologyNetherlands Heart Journal
- 2018
The percentage of high-risk NSTE-ACS patients undergoing CAG and EIS has increased in the last decade and patients with a higher risk profile are less likely to undergo EIS, however, no difference in outcome after 30 days and 1 year was found after multivariate adjustment for this higher risk.
Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment: The EARLY Randomized Trial.
- MedicineJACC. Cardiovascular interventions
- 2020
References
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Optimal Timing of Coronary Invasive Strategy in Non–ST-Segment Elevation Acute Coronary Syndromes
- MedicineAnnals of Internal Medicine
- 2013
There is insufficient evidence either in favor of or against an early invasive approach in the NSTE-ACS population, and a more definitive RCT is warranted to guide clinical practice.
Long-term outcome of a routine versus selective invasive strategy in patients with non-ST-segment elevation acute coronary syndrome a meta-analysis of individual patient data.
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Timing of Coronary Invasive Strategy in Non-ST-Segment Elevation Acute Coronary Syndromes and Clinical Outcomes: An Updated Meta-Analysis.
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Timing of invasive strategy in NSTE-ACS patients and effect on clinical outcomes: A systematic review and meta-analysis of randomized controlled trials.
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Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysis.
- MedicineJAMA
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In NSTE ACS, an invasive strategy has a comparable benefit in men and high-risk women for reducing the composite end point of death, MI, or rehospitalization with ACS, and evidence supporting the new guideline recommendation for a conservative strategy in low- risk women is provided.
An invasive or conservative strategy in patients with diabetes mellitus and non-ST-segment elevation acute coronary syndromes: a collaborative meta-analysis of randomized trials.
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- 2012
The impact of increased age on outcome from a strategy of early invasive management and revascularisation in patients with acute coronary syndromes: retrospective analysis study from the ACACIA registry
- MedicineBMJ Open
- 2012
Following presentation with ACS, elderly patients are less likely to receive evidence-based medical therapies, to be considered for an early invasive strategy and be revascularised, and the absolute accrued benefit appears to be higher in elderly patients.
Early versus delayed percutaneous coronary intervention for patients with non‐ST segment elevation acute coronary syndrome: A meta‐analysis of randomized controlled clinical trials
- MedicineCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
- 2013
In NSTE‐ACS patients early PCI doesn't reduce the odds of the composite endpoint of death or non‐fatal MI at 30 day, and this strategy is associated with lower odds of bleeding and higher odds of repeat revascularization at 30 days than a strategy of delayed PCI.