Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials

@article{Jobs2017OptimalTO,
  title={Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials},
  author={Alexander Jobs and Shamir R. Mehta and Gilles Montalescot and Eric Vicaut and Arnoud WJ van’t Hof and Erik A Badings and Franz-Josef Neumann and Adnan Kastrati and Alessandro Sciahbasi and Paul-Georges Reuter and Fr{\'e}d{\'e}ric Lapostolle and Aleksandra Milo{\vs}evi{\'c} and Goran Stankovi{\'c} and Dejan Milasinovic and Reinhard Vonthein and Steffen Desch and Holger Thiele},
  journal={The Lancet},
  year={2017},
  volume={390},
  pages={737-746}
}
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118 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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118 Citations

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References

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There is insufficient evidence either in favor of or against an early invasive approach in the NSTE-ACS population, and a more definitive RCT is warranted to guide clinical practice.
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Early versus delayed percutaneous coronary intervention for patients with non‐ST segment elevation acute coronary syndrome: A meta‐analysis of randomized controlled clinical trials
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TLDR
In NSTE‐ACS patients early PCI doesn't reduce the odds of the composite endpoint of death or non‐fatal MI at 30 day, and this strategy is associated with lower odds of bleeding and higher odds of repeat revascularization at 30 days than a strategy of delayed PCI.
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