Optimal sequence of adjuvant endocrine and radiation therapy in early-stage breast cancer - A systematic review.

@article{McGee2018OptimalSO,
  title={Optimal sequence of adjuvant endocrine and radiation therapy in early-stage breast cancer - A systematic review.},
  author={Sharon F. McGee and Sasha Mazzarello and J M Caudrelier and M A G Lima and Brian Hutton and Marta Sienkiewicz and Carol Stober and R. Otero Fernandes and Mohammed Fadhil Ibrahim and Lisa A Vandermeer and John Frederick Hilton and Risa Shorr and Dean Fergusson and Mark Clemons},
  journal={Cancer treatment reviews},
  year={2018},
  volume={69},
  pages={
          132-142
        }
}
IMPORTANCE Clinical equipoise exists around the optimal time to start adjuvant endocrine therapy in patients who will receive post-operative radiotherapy for breast cancer. Concerns continue to exist regarding potential reduced efficacy, or increased toxicity, when radiation, and endocrine therapy are administered concurrently. OBJECTIVE To perform a systematic review of studies comparing outcomes between sequential and concurrent adjuvant radiation and endocrine therapy in early-stage breast… CONTINUE READING
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