Optimal sampling for pedigree analysis: sequential schemes for sibships.

@article{Thompson1981OptimalSF,
  title={Optimal sampling for pedigree analysis: sequential schemes for sibships.},
  author={E. A. Thompson},
  journal={Biometrics},
  year={1981},
  volume={37 2},
  pages={313-25}
}
Methods for inferring the mode of inheritance of a trait from familial data are becoming widely used. It is therefore important to assess alternative procedures for the collection of the relevant data. Cannings and Thompson (1977, Clinical Genetics 12, 208-212) and Thompson and Cannings (1979. In Genetic Analysis of Common Diseases, 363-382, New York: Liss) have advocated sequential schemes on the grounds that these admit simple methods for the correction of the likelihood function for… CONTINUE READING