Optimal prescription method for cancer chemotherapy.

@article{Vriesendorp1985OptimalPM,
  title={Optimal prescription method for cancer chemotherapy.},
  author={Huib M. Vriesendorp},
  journal={Experimental hematology},
  year={1985},
  volume={13 Suppl 16},
  pages={
          57-63
        }
}
A reexamination of the guidelines for prescriptions for cancer chemotherapy suggests that the use of body surface area (BSA) offers a simplification that may be open to some question. The same drug dose per BSA will give approximately the same toxicity in different age groups and species. This simplification appears to be fortuitous, however, as BSA does not correlate with the dose-limiting target cells, i.e., the hemopoietic stem cell. In patients with an unmodified hemopoietic system, body… CONTINUE READING

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