Optimal medical therapy with or without PCI for stable coronary disease.

@article{Boden2007OptimalMT,
  title={Optimal medical therapy with or without PCI for stable coronary disease.},
  author={William E. Boden and Robert A. O'rourke and Koon K Teo and Pamela M. Hartigan and David J. Maron and William J. Kostuk and Merril L. Knudtson and Marcin Dada and Paul Casperson and Crystal L. Harris and Bernard R. Chaitman and Leslee J. Shaw and Gilbert Gosselin and Shah Nawaz and Lawrence M. Title and Gerald T. Gau and Alvin S. Blaustein and David C. Booth and Eric R. Bates and John A. Spertus and Daniel S. Berman and G. B. John Mancini and William S. Weintraub},
  journal={The New England journal of medicine},
  year={2007},
  volume={356 15},
  pages={
          1503-16
        }
}
BACKGROUND In patients with stable coronary artery disease, it remains unclear whether an initial management strategy of percutaneous coronary intervention (PCI) with intensive pharmacologic therapy and lifestyle intervention (optimal medical therapy) is superior to optimal medical therapy alone in reducing the risk of cardiovascular events. METHODS We conducted a randomized trial involving 2287 patients who had objective evidence of myocardial ischemia and significant coronary artery disease… 

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