Optimal hybrid sequencing and assembly: Feasibility conditions for accurate genome reconstruction and cost minimization strategy

Abstract

Recent advances in high-throughput genome sequencing technologies have enabled the systematic study of various genomes by making whole genome sequencing affordable. Modern sequencers generate a huge number of small sequence fragments called reads, where the read length and the per-base sequencing cost depend on the technology used. To date, many hybrid… (More)
DOI: 10.1016/j.compbiolchem.2017.03.016

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Cite this paper

@article{Chen2017OptimalHS, title={Optimal hybrid sequencing and assembly: Feasibility conditions for accurate genome reconstruction and cost minimization strategy}, author={Chun-Chi Chen and Noushin Ghaffari and Xiaoning Qian and Byung-Jun Yoon}, journal={Computational biology and chemistry}, year={2017}, volume={69}, pages={153-163} }