Optimal dosing of atypical antipsychotics in adults: a review of the current evidence.

@article{Citrome2002OptimalDO,
  title={Optimal dosing of atypical antipsychotics in adults: a review of the current evidence.},
  author={Leslie Citrome and J. V. Volavka},
  journal={Harvard review of psychiatry},
  year={2002},
  volume={10 5},
  pages={280-91}
}
This review describes dosing strategies used to optimize the beneficial effects of atypical antipsychotic medications. Differences between manufacturers' recommended dosing and actual clinical practice are reconciled using evidence from pivotal double-blind randomized registration studies, other randomized clinical trials, case series, and case reports. With clozapine and perhaps olanzapine, plasma levels are correlated with therapeutic response; with risperidone, plasma levels are not… CONTINUE READING

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