Optimal contact definition for reconstruction of Contact Maps

  title={Optimal contact definition for reconstruction of Contact Maps},
  author={Jose M. Duarte and Rajagopal Sathyapriya and Henning Stehr and Ioannis Filippis and Michael Lappe},
  booktitle={BMC Bioinformatics},
Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being preferred by a number of researchers for the description and study of protein structures. Inspired by the model's simplicity many groups have dedicated a considerable amount of effort towards contact prediction as a proxy for protein structure prediction. However a contact map's biological interest is subject to the availability of… CONTINUE READING