Optimal bone mechanical and material properties require a functional glucagon-like peptide-1 receptor.

@article{Mabilleau2013OptimalBM,
  title={Optimal bone mechanical and material properties require a functional glucagon-like peptide-1 receptor.},
  author={Guillaume Mabilleau and Aleksandra Mieczkowska and Nigel Irwin and Peter Raymond Flatt and Daniel Chappard},
  journal={The Journal of endocrinology},
  year={2013},
  volume={219 1},
  pages={59-68}
}
Bone is permanently remodeled by a complex network of local, hormonal, and neuronal factors that affect osteoclast and osteoblast biology. Among these factors, a role for gastrointestinal hormones has been proposed based on the evidence that bone resorption dramatically falls after a meal. Glucagon-like peptide-1 (GLP1) is one of these gut hormones, and despite several reports suggesting an anabolic effect of GLP1, or its stable analogs, on bone mass, little is known about the effects of GLP1… CONTINUE READING

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