Optimal blood glucose levels while using insulin to minimize the size of infarction in focal cerebral ischemia.

@article{Zhu2004OptimalBG,
  title={Optimal blood glucose levels while using insulin to minimize the size of infarction in focal cerebral ischemia.},
  author={Chang Zhen Zhu and Roland N. Auer},
  journal={Journal of neurosurgery},
  year={2004},
  volume={101 4},
  pages={664-8}
}
OBJECT Insulin has been shown to ameliorate cerebral necrosis in global and, more recently, in focal cerebral ischemia. The goal of this study was to determine the relationship between this neuroprotective effect and blood sugar levels in a rat model of focal ischemia. METHODS Thirty-four rats were subjected to 80 minutes of transient middle cerebral artery occlusion at a mean arterial blood pressure of 60 mm Hg and a temperature of 37 degrees C. Insulin (3.5 IU/kg) was administered 1 hour… CONTINUE READING
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