Optimal and efficient crossover designs under different assumptions about the carryover effects.

@article{Hedayat2003OptimalAE,
  title={Optimal and efficient crossover designs under different assumptions about the carryover effects.},
  author={A. Sadam Hedayat and John Stufken},
  journal={Journal of biopharmaceutical statistics},
  year={2003},
  volume={13 3},
  pages={519-28}
}
In certain studies it is desirable or necessary that a subject, such as a patient in a medical trial, receive a treatment in each period. This facilitates a within-subject comparison of the treatments. Designs for studies of this type are called crossover designs or repeated measurements designs. If there are s subjects in p periods, the design should specify which of the t treatments is assigned to subject j in period i, i = 1,... ,p,j = 1,..., s. Equivalently we may think of a design as… CONTINUE READING

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