Optimal administration schedules of the newly synthesized platinum analog NK121 and bleomycin analog NK313 in nude mice with squamous cell carcinoma.

@article{Kanazawa1992OptimalAS,
  title={Optimal administration schedules of the newly synthesized platinum analog NK121 and bleomycin analog NK313 in nude mice with squamous cell carcinoma.},
  author={Hiroshi Kanazawa and Hidetaka Yokoe and Ken-ichi Takahashi and Koichiro Sato},
  journal={Head & neck},
  year={1992},
  volume={14 1},
  pages={38-43}
}
To determine the optimal administration schedules of the newly synthesized, less nephrotoxic platinum analog NK121 and less pneumotoxic bleomycin analog NK313, the antitumor effects of 2 different injection schedules, (1) single injections on days 1, 5, and 9, (2) continuous infusion for 7 days, were compared in nude mice bearing human squamous cell… CONTINUE READING