Optimal Transport Features for Morphometric Population Analysis

  title={Optimal Transport Features for Morphometric Population Analysis},
  author={Samuel Gerber and Marc Niethammer and Ebrahim Ebrahim and Joseph Piven and Stephen R. Dager and M. Styner and Stephen R. Aylward and Andinet Enquobahrie},
Brain pathologies often manifest as partial or complete loss of tissue. The goal of many neuroimaging studies is to capture the location and amount of tissue changes with respect to a clinical variable of interest, such as disease progression. Morphometric analysis approaches capture local di ff erences in the distribution of tissue or other quantities of interest in relation to a clinical variable. We propose to augment morphometric analysis with an additional feature extraction step based on… 
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Frontal lobe degeneration of non-Alzheimer type. I. Neuropathology.

  • A. Brun
  • Psychology, Medicine
    Archives of gerontology and geriatrics
  • 1987