Optimal Tmax threshold for predicting penumbral tissue in acute stroke.

@article{Olivot2009OptimalTT,
  title={Optimal Tmax threshold for predicting penumbral tissue in acute stroke.},
  author={J-M. Olivot and M Mlynash and Vincent N Thijs and Stephanie M Kemp and Maarten G Lansberg and Lawrence R. Wechsler and Roland Bammer and M P Marks and Gregory W. Albers},
  journal={Stroke},
  year={2009},
  volume={40 2},
  pages={
          469-75
        }
}
BACKGROUND AND PURPOSE We sought to assess whether the volume of the ischemic penumbra can be estimated more accurately by altering the threshold selected for defining perfusion-weighting imaging (PWI) lesions. METHODS DEFUSE is a multicenter study in which consecutive acute stroke patients were treated with intravenous tissue-type plasminogen activator 3 to 6 hours after stroke onset. Magnetic resonance imaging scans were obtained before, 3 to 6 hours after, and 30 days after treatment… CONTINUE READING

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