Optimal Control of a Time Delayed HIV-1 Infection Model

  title={Optimal Control of a Time Delayed HIV-1 Infection Model},
  author={Nigar Ali and Muhammad Ikhlaq Chohan and Gul Zaman},
In this paper, an optimal control problem of HIV infection model of delay differential equations is taken into account. Then we set a control function which represents the efficiency of reverse transcriptase inhibitors. Objective functional is constructed to minimize the virus concentration as well as treatment costs.Adjoint system is derived using Pontryagins Maximum Principle. Optimality system is calculated and numerical simulation is carried out to illustrate the theoretical results… CONTINUE READING