Optimal Antagonism of the Renin-Angiotensin-Aldosterone System

@article{Werner2010OptimalAO,
  title={Optimal Antagonism of the Renin-Angiotensin-Aldosterone System},
  author={Christian Werner and Janine Poess and Professor Dr med Michael B{\"o}hm},
  journal={Drugs},
  year={2010},
  volume={70},
  pages={1215-1230}
}
The cardiovascular and cardiorenal disease continuum comprises the transition from cardiovascular risk factors to endothelial dysfunction and atherosclerosis, to clinical complications such as myocardial infarction (MI) and stroke, to the development of persistent target-organ damage and, ultimately, to chronic congestive heart failure (CHF), end-stage renal disease or premature death. The renin-angiotensin-aldosterone system (RAAS) is involved in all steps along this pathway, and RAAS blockade… CONTINUE READING

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