Corpus ID: 52266214

Optim zing To-Dow A alysis of Proteins on Orbitrap Fusion TM Lumos TM Tribrid TM Mass Spectromet r

@inproceedings{Sharma2015OptimZT,
  title={Optim zing To-Dow A alysis of Proteins on Orbitrap Fusion TM Lumos TM Tribrid TM Mass Spectromet r},
  author={Seema Sharma and P. Mallick and T. Stoyanova and C. Mullen and Chad R Weisbrod and Jesse D. Canterbury and D. Horn and V. Zabrouskov},
  year={2015}
}
  • Seema Sharma, P. Mallick, +5 authors V. Zabrouskov
  • Published 2015
  • Top-down analysis allows the measurement of intact protein masses and provides information on post-translational modifications, proteoforms as well as the protein sequence via fragmentation of the intact proteins in the mass spectrometer. In this work, we present top down analysis of intact proteins on the Orbitrap Fusion Lumos mass spectrometer, equipped with the higher capacity ETD HD fragmentation mode and benefitting from improved transmission of ions into the Orbitrap analyzer afforded by… CONTINUE READING