Optical signals from neurons with internally applied voltage-sensitive dyes.

@article{Antic1995OpticalSF,
  title={Optical signals from neurons with internally applied voltage-sensitive dyes.},
  author={Srdjan Antic and Dejan Zecevic},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1995},
  volume={15 2},
  pages={1392-405}
}
We carried out experiments to monitor optically the generation and spread of action potentials and subthreshold potentials in the processes of individual neurons in ganglia of the snail, Helix aspersa. The neurons were selectively stained by intracellular pressure injection of voltage-sensitive dyes. Optical signals were detected by a system for fast, multiple-site optical monitoring, utilizing a silicon photodiode array. After testing 30 voltage-sensitive dyes using absorption, we concluded… CONTINUE READING

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