Optical recording of synaptic potentials from processes of single neurons using intracellular potentiometric dyes.

@article{Grinvald1987OpticalRO,
  title={Optical recording of synaptic potentials from processes of single neurons using intracellular potentiometric dyes.},
  author={Amiram Grinvald and Brian M. Salzberg and V Lev-Ram and Rina Hildesheim},
  journal={Biophysical journal},
  year={1987},
  volume={51 4},
  pages={643-51}
}
To record post synaptic potentials or electrical activity from processes of single cells in a central nervous system (CNS) preparation in situ, voltage sensitive dyes can be injected intracellularly, thereby staining only the cell under investigation. We report the structure, evaluation, and synthesis of 11 fluorescent styryl dyes developed for iontophoretic injection. The optical signals that represent small synaptic potentials from single processes of iontophoretically injected cells are… CONTINUE READING