Optical immunoassay for rapid detection of group A beta-hemolytic streptococci. Should culture be replaced?

Abstract

OBJECTIVE To evaluate an optical immunoassay rapid antigen test to detect group A beta-hemolytic streptococci directly from throat swab specimens. DESIGN Criterion standard with "blinded" comparison. Double-swab pharyngeal samples were obtained; one swab was cultured and the other was used for the rapid antigen test. SETTING Microbiology laboratory in a… (More)

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