Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress.

@article{Sepehr2012OpticalIO,
  title={Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress.},
  author={R. Sepehr and Kevin S. Staniszewski and Sepideh Maleki and Elizabeth R. Jacobs and Said H. Audi and Mahsa Ranji},
  journal={Journal of biomedical optics},
  year={2012},
  volume={17 4},
  pages={046010}
}
Ventilation with enhanced fractions of O(2) (hyperoxia) is a common and necessary treatment for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung injury. Ischemia-reperfusion (IR) injury of lung tissue is common in lung transplant or crush injury to the chest. These conditions are associated with apoptosis and decreased survival of lung tissue. The objective of this work is to use cryoimaging to evaluate the effect of exposure to hyperoxia and IR injury on… CONTINUE READING

From This Paper

Figures and tables from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Pulmonary Vasculature Redox Signaling in Health and Disease

Advances in Experimental Medicine and Biology • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Schoener, “High and low energy states of cytochromes, II. in submitochondrial particles,

B. Chance, C. P. Lee
J. Biol. Chem. 241(20), • 1966
View 4 Excerpts
Highly Influenced

Differential responses of targeted lung redox enzymes to rat exposure to 60 or 85% oxygen,

Z. Gan
J. Appl. Physiol • 2011
View 4 Excerpts
Highly Influenced

The association of near-infrared spectroscopy derived tissue oxygenation measurements with sepsis syndromes, organ dysfunction, and mortality in emergency department patients with sepsis,

N. I. Shapiro
Crit. Care 15(5), • 2011
View 1 Excerpt

The role of TLR4 and HMGB1 in the ischemia/ reperfusion-mediated mitochondrial dysfunction,

A. Leke-Tambo
Chest • 2011
View 1 Excerpt

benchto-bedside real-time optical monitoring system,” J

A. Mayevsky et al., “Mitochondrial function, tissue vitality
Biomed. Opt. 16(6), 067004 • 2011
View 1 Excerpt

Similar Papers

Loading similar papers…