Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells.

@article{Alhallak2017OpticalIO,
  title={Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells.},
  author={Kinan Alhallak and Samir V. Jenkins and David E Lee and Nicholas P Greene and Kyle P Quinn and Robert J Griffin and Ruud P M Dings and Narasimhan Rajaram},
  journal={Journal of biomedical optics},
  year={2017},
  volume={22 6},
  pages={
          60502
        }
}
Radiation resistance remains a significant problem for cancer patients, especially due to the time required to definitively determine treatment outcome. For fractionated radiation therapy, nearly 7 to 8 weeks can elapse before a tumor is deemed to be radiation-resistant. We used the optical redox ratio of FAD / ( FAD + NADH ) to identify early metabolic… CONTINUE READING