Optical coherence tomography for assessment of epithelialization in a human ex vivo wound model.

@article{Glinos2017OpticalCT,
  title={Optical coherence tomography for assessment of epithelialization in a human ex vivo wound model.},
  author={George D. Glinos and Sebastian H Verne and Adam Souhail Aldahan and Liang Liang and Keyvan Nouri and Sharon J. Elliot and Marilyn K. Glassberg and Delia Cabrera DeBuc and Tulay Koru-Sengul and Marjana Tomic-Canic and Irena Pastar},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2017},
  volume={25 6},
  pages={
          1017-1026
        }
}
The ex vivo human skin wound model is a widely accepted model to study wound epithelialization. Due to a lack of animal models that fully replicate human conditions, the ex vivo model is a valuable tool to study mechanisms of wound reepithelialization, as well as for preclinical testing of novel therapeutics. The current standard for assessment of wound healing in this model is histomorphometric analysis, which is labor intensive, time consuming, and requires multiple biological and technical… CONTINUE READING

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Fluorescent cell tracer dye permits real-time assessment of re-epithelialization in a serum-free ex vivo human skin wound assay.

  • Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2019
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