Optical coherence tomography: a review of clinical development from bench to bedside.

@article{Zysk2007OpticalCT,
  title={Optical coherence tomography: a review of clinical development from bench to bedside.},
  author={Adam M Zysk and F. Nguyen and Amy L. Oldenburg and Daniel L. Marks and Stephen A. Boppart},
  journal={Journal of biomedical optics},
  year={2007},
  volume={12 5},
  pages={
          051403
        }
}
Since its introduction, optical coherence tomography (OCT) technology has advanced from the laboratory bench to the clinic and back again. Arising from the fields of low coherence interferometry and optical time- and frequency-domain reflectometry, OCT was initially demonstrated for retinal imaging and followed a unique path to commercialization for clinical use. Concurrently, significant technological advances were brought about from within the research community, including improved laser… Expand
Optical coherence tomography today: speed, contrast, and multimodality
TLDR
Various multimodal imaging modalities with OCT incorporated are reviewed, in that these multi-modal implementations can synergistically compensate for the fundamental limitations of OCT when it is used alone. Expand
Functional optical coherence tomography: principles and progress.
TLDR
This review emphasizes the newer techniques of SOCT and molecular imaging OCT, which show excellent potential for clinical application but have yet to be well reviewed in the literature. Expand
Towards freehand image acquisition in optical coherence tomography
TLDR
A cross-correlation-based algorithm for OCT data acquisition that does not rely on precision beam scanning is developed that essentially reconstructs an image by assembling A scans that are Figure 1. Expand
Advances of full-field optical coherence tomography (FFOCT) for clinical applications and developmental biology
TLDR
A compact FFOCT system has been tested under clinical conditions for imaging breast lesions up to 1 cm² as well as core-needle biopsies with encouraging preliminary results, nonetheless endogenous contrast enhancements are necessary. Expand
Optical coherence tomography in biomedical research
TLDR
An outline of the state of the art and novel trends of innovative OCT approaches in biomedical research in which the main focus is on applications in fundamental research and pre-clinical utilization is given. Expand
Review of optical coherence tomography in oncology
TLDR
The evolution of OCT technologies for the clinical application of OCT in surgical and noninvasive interventional oncology procedures is reviewed and a discussion of the future directions for OCT technologies are discussed, with particular emphasis on their applications in oncologists. Expand
Clinical applications of optical coherence tomography in urology
TLDR
Current clinical applications in urology, particularly in bladder, urether, and kidney are reviewed, which mainly focus on cancer detection and staging based on tissue morphology, image contrast, and OCT backscattering. Expand
Near Infrared Spectroscopy in Optical Coherence Tomography
Optical coherence tomography (OCT) is a technique that is able to provide cross section views of tissue layers. This fast and non-invasive method is widely used in clinical applications for theExpand
Methods and algorithms for optical coherence tomography-based angiography: a review and comparison
TLDR
The purpose of this review is to help readers understand and select appropriate OCT angiography algorithm for use in specific applications and it is found that the method that utilizes complex OCT signal to contrast retinal blood flow delivers the best performance among all the algorithms in terms of image contrast and vessel connectivity. Expand
High-speed optical coherence tomography: basics and applications.
TLDR
The fundamental limitations and advantages of time-domain and Fourier-domain interferometric detection methods are discussed, and new perspectives on functional imaging with the use of state-of-the-art high-speed OCT technology are demonstrated. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 381 REFERENCES
Clinical imaging with optical coherence tomography.
TLDR
The current technology of optical coherence tomography (OCT) is reviewed and an overview of recent OCT studies in gastroenterology and cardiology is provided. Expand
Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies
TLDR
The ability of OCT to image tissue microstructure at high resolutions makes it a potentially powerful technology for minimally invasive assessment of the gastrointestinal tract and the evaluation of early neoplastic changes. Expand
Retinal assessment using optical coherence tomography
TLDR
A brief look in the past of OCT is taken and the key basic physical principles of this imaging technology are explained and the future directions of this exceptional technique are commented on. Expand
Advances in optical coherence tomography imaging for dermatology.
TLDR
Combining the previously described structural and Doppler imaging functions with polarization-sensitive imaging increases the utility of the technique for rapid, non-invasive investigations in the skin. Expand
Optical coherence tomography for optical biopsy. Properties and demonstration of vascular pathology.
TLDR
OCT represents a promising new technology for imaging vascular microstructure with a level of resolution not previously achieved with the use of other imaging modalities, and can be performed with a catheter integrated with a relatively inexpensive optical fiber. Expand
Optical biopsy in human gastrointestinal tissue using optical coherence tomography.
TLDR
The ability of OCT to provide high-resolution in situ imaging of gastrointestinal microstructure, without the need for excisional biopsy, suggests the feasibility of using OCT as a powerful diagnostic imaging technology, which can be integrated with conventional endoscopy. Expand
In vivo endoscopic optical coherence tomography of the human gastrointestinal tract--toward optical biopsy.
TLDR
This is the first clinical study of OCT during routine endoscopy obtaining high resolution images of the normal esophageal, gastric, and colonic mucosa and indicates that OCT images may become comparable to mucosal histological findings. Expand
Ultrahigh resolution optical biopsy with endoscopic optical coherence tomography.
TLDR
The ability of ultrahigh resolution endoscopic OCT to image tissue morphology at an unprecedented resolution in vivo advances the development of OCT as a potential imaging tool for the early detection of neoplastic changes in biological tissue. Expand
Optical coherence tomography.
The optical coherence tomograph is a new, noninvasive technical device that can obtain cross-sectional, high-resolution images-optical coherence tomographs (OCT)-of the retina. This instrumentExpand
Optical Coherence Tomography: Feasibility for Basic Research and Image-guided Surgery of Breast Cancer
TLDR
The results illustrate the potential of OCT for a wide range of basic research studies and for intra-operative image-guidance to identify foci of tumor cells within surgical margins during the surgical treatment of breast cancer. Expand
...
1
2
3
4
5
...