Optical bioluminescence imaging of human ES cell progeny in the rodent CNS.

@article{Bradbury2007OpticalBI,
  title={Optical bioluminescence imaging of human ES cell progeny in the rodent CNS.},
  author={Michelle S Bradbury and Georgia Panagiotakos and Bill K Chan and Mark J. Tomishima and Pat Zanzonico and Jelena Vider and Vladimir Ponomarev and Lorenz P Studer and Viviane S Tabar},
  journal={Journal of neurochemistry},
  year={2007},
  volume={102 6},
  pages={2029-2039}
}
Pre-clinical efforts of grafting human embryonic stem cell (hESC)-derived neural precursors have been hampered by problems ranging from graft rejection to overgrowth and tumor formation. The ability to detect such potential complications sensitively and reliably in clinically relevant contexts will rest upon the implementation of suitable non-invasive imaging technologies for continuously probing graft survival, proliferation, and migration. Neural precursors were transduced ex vivo using a… CONTINUE READING
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