Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo.

Abstract

In the naïve adult rodent eye cell proliferation does not occur. The aim of this in vivo study was to evaluate if quiescent putative progenitor-like cells within the adult mouse eye can be activated by optic nerve (ON) injury. For a comprehensive analysis, three areas were assessed: the ON, the neural retina, and the ciliary body (CB). Two lesion types were… (More)
DOI: 10.1016/j.expneurol.2009.05.008

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