Optic Pathway Gliomas in Neurofibromatosis Type 1.

@article{Campen2018OpticPG,
  title={Optic Pathway Gliomas in Neurofibromatosis Type 1.},
  author={Cynthia Jane Campen and David H Gutmann},
  journal={Journal of child neurology},
  year={2018},
  volume={33 1},
  pages={
          73-81
        }
}
Neurofibromatosis type 1 (NF1) is one of the most common brain tumor predisposition syndromes, in which affected children are prone to the development of low-grade gliomas. While NF1-associated gliomas can be found in several brain regions, the majority arise in the optic nerves, chiasm, tracts, and radiations (optic pathway gliomas; OPGs). Owing to their location, 35-50% of affected children present with reduced visual acuity. Unfortunately, despite tumor stabilization following chemotherapy… CONTINUE READING