Optic Nerve Enlargement in Krabbe Disease: A Pathophysiologic and Clinical Perspective

@article{Hussain2011OpticNE,
  title={Optic Nerve Enlargement in Krabbe Disease: A Pathophysiologic and Clinical Perspective},
  author={Syed A. Hussain and Holly H. Zimmerman and O. A. Abdul-Rahman and S. M. Hussaini and C. Parker and Majid Khan},
  journal={Journal of Child Neurology},
  year={2011},
  volume={26},
  pages={642 - 644}
}
  • Syed A. Hussain, Holly H. Zimmerman, +3 authors Majid Khan
  • Published 2011
  • Medicine
  • Journal of Child Neurology
  • Krabbe disease is an infantile-onset progressive leukodystrophy. The classic presentation includes excessive irritability, muscle hypertonicity, developmental delay, failure to thrive, peripheral neuropathy, seizures, and optic nerve atrophy. The authors report a rare case of optic nerve enlargement early in infantile Krabbe disease. Their case demonstrates proximal prechiasmatic enlargement of the nerves. They discuss the pathophysiological and clinical correlation of optic nerve enlargement… CONTINUE READING
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