OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens

@inproceedings{Aljayyoussi2016OptiMalPKAI,
  title={OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens},
  author={Ghaith Aljayyoussi and Katherine Kay and Stephen A Ward and Giancarlo A Biagini},
  booktitle={Malaria Journal},
  year={2016}
}
BackgroundThe search for highly effective anti-malarial therapies has gathered pace and recent years have seen a number of promising single and combined therapies reach the late stages of development. A key drug development challenge is the need for early assessment of the clinical utility of new drug leads as it is often unclear for developers whether efforts should be focused on efficacy or metabolic stability/exposure or indeed whether the continuation of iterative QSAR (quantitative… CONTINUE READING
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