Opsonizing and bactericidal effects of normal human serum on nontypable Haemophilus influenzae.

@article{Musher1983OpsonizingAB,
  title={Opsonizing and bactericidal effects of normal human serum on nontypable Haemophilus influenzae.},
  author={Daniel M. Musher and M Hague-Park and Robert E. Baughn and Richard J. Wallace and Benjamin Cowley},
  journal={Infection and immunity},
  year={1983},
  volume={39 1},
  pages={297-304}
}
The observation that nontypable (NT) Haemophilus influenzae causes serious infection in adults has stimulated interest in mechanisms that may protect the human host against NT H. influenzae infection. Incubating NT H. influenzae with normal human serum (NHS) caused dose- and time-dependent killing that varied with the individual NHS and NT H. influenzae. Adsorption of NHS with NT H. influenzae removed bactericidal activity against the adsorbing isolate but not necessarily that against others… CONTINUE READING
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