Opsoclonus-ataxia due to childhood neural crest tumors: a chronic neurologic syndrome.

@article{Mitchell1990OpsoclonusataxiaDT,
  title={Opsoclonus-ataxia due to childhood neural crest tumors: a chronic neurologic syndrome.},
  author={Wendy G Mitchell and Samuel Robert Snodgrass},
  journal={Journal of child neurology},
  year={1990},
  volume={5 2},
  pages={153-8}
}
Five children with subacute or acute onset of cerebellar ataxia and opsoclonus are described. Two had cerebrospinal fluid pleocytosis at the onset of ataxia and were initially thought to have acute parainfectious cerebellar ataxia of childhood. All were found to have tumors of neural crest origin (two neuroblastomas, three ganglioneuroblastomas). Tumors were small and only found by computed tomographic techniques. Urinary catecholamine metabolites were elevated in only two of the patients. Four… CONTINUE READING

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