Opsin accumulation in photoreceptor inner segment plasma membranes of dystrophic RCS rats.

@article{Nir1987OpsinAI,
  title={Opsin accumulation in photoreceptor inner segment plasma membranes of dystrophic RCS rats.},
  author={Izhak Nir and G Sagie and David S. Papermaster},
  journal={Investigative ophthalmology & visual science},
  year={1987},
  volume={28 1},
  pages={
          62-9
        }
}
Opsin localization in photoreceptor plasma membrane was studied in 10- to 30-day-old dystrophic RCS rats. Preembedding cytochemical procedures with antiopsin antibodies and electron microscopy were employed. In the second postnatal week, opsin was sequestered to the outer segment plasma membrane in affected rat retinas. This distribution resembled that observed in the photoreceptors of normal rats at this age. As unphagocytosed debris accumulated in the subretinal space, the outer segments… CONTINUE READING
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