Opposite effects of α-lipoic acid on antioxidation and long-term potentiation in control and chronically lead-exposed rats

@article{Wang2008OppositeEO,
  title={Opposite effects of α-lipoic acid on antioxidation and long-term potentiation in control and chronically lead-exposed rats},
  author={Huili Wang and Xiang-tao Chen and Shu-Ting Yin and Jin Liu and Ming-liang Tang and Chuan-yun Wu and Di-yun Ruan},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2008},
  volume={378},
  pages={303-310}
}
Among the developmental changes identified in rats exposed to lead are impairments in long-term potentiation (LTP) in the hippocampus and changes in the levels of reactive oxygen species (ROS) in cells and some soft tissues. α-Lipoic acid (LA) has been reported to be highly effective in improving the thiol capacity of the cells and in reducing lead-induced… CONTINUE READING