Opposing roles for dopamine D1- and D2-like receptors in discrete cue-induced reinstatement of food seeking.

@article{Ball2011OpposingRF,
  title={Opposing roles for dopamine D1- and D2-like receptors in discrete cue-induced reinstatement of food seeking.},
  author={Kevin T. Ball and Tarra A Combs and Denise N Beyer},
  journal={Behavioural brain research},
  year={2011},
  volume={222 2},
  pages={390-3}
}
We used a rat reinstatement model to test the involvement of dopamine D1- and D2-like receptors in discrete cue-induced reinstatement of food seeking. At a dose that did not alter responding during food self-administration, the D1-like antagonist SCH-23390 blocked reinstatement of food seeking, while the D2-like antagonist eticlopride significantly increased reinstatement responding. Thus, these results establish opposing roles for D1- and D2-like receptors in discrete cue-induced relapse to… CONTINUE READING

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The role of prefrontal cortex D 1 - like and D 2 - like receptors in cocaine - seeking behavior in rats

  • AL Chausmer, A Ettenberg, W Sun, GV Rebec
  • Psychopharmacology ( Berl )
  • 2011

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