Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals


Ras p21 signaling is involved in multiple aspects of growth, differentiation, and stress response [1-2]. There is evidence pointing to superoxides as relays of Ras signaling messages. Chemicals with antioxidant activity suppress Ras-induced DNA synthesis. The inhibition of Ras significantly reduces the production of superoxides by the NADPH-oxidase complex… (More)
DOI: 10.1016/S0960-9822(01)00159-2


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