Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.

@article{Esposito2007OpposingCO,
  title={Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.},
  author={Giuseppe Esposito and Teresa Iuvone and Claudia Savani and Caterina Scuderi and Daniele De Filippis and Michele Papa and Vincenzo Di Marzo and Luca Steardo},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2007},
  volume={322 3},
  pages={1144-52}
}
Beside cytotoxic mechanisms impacting on neurons, amyloid beta (A beta)-induced astroglial activation is operative in Alzheimer's disease brain, suggesting that persistent inflammatory response may have a role in the illness and that positive results may be achieved by curbing the astroglial reaction. Because the role of the endocannabinoid system could represent a promising field of research, the present study conducted in vitro and in vivo experiments to assess this system. C6 rat astroglioma… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…