Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.

@article{Pathania2009OpportunitiesID,
  title={Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.},
  author={Divya Pathania and Melissa Millard and Nouri Neamati},
  journal={Advanced drug delivery reviews},
  year={2009},
  volume={61 14},
  pages={1250-75}
}
Cancer cells are characterized by self-sufficiency in the absence of growth signals, their ability to evade apoptosis, resistance to anti-growth signals, sustained angiogenesis, uncontrolled proliferation, and invasion and metastasis. Alterations in cellular bioenergetics are an emerging hallmark of cancer. The mitochondrion is the major organelle… CONTINUE READING