Opportunities for improving the therapeutic ratio for patients with sarcoma.

@article{Wunder2007OpportunitiesFI,
  title={Opportunities for improving the therapeutic ratio for patients with sarcoma.},
  author={Jay S Wunder and Torsten O. Nielsen and Robert G Maki and Brian O'Sullivan and Benjamin A Alman},
  journal={The Lancet. Oncology},
  year={2007},
  volume={8 6},
  pages={513-24}
}
Sarcomas are mesenchymal cancers, which, in many cases, have distinctive molecular features. Limb-sparing surgery delivered at specialised sarcoma centres as part of a multidisciplinary approach has become the standard treatment for most patients and usually provides excellent local control. Preoperative treatment with chemotherapy is most common for patients with bone sarcomas. The ideal sequence of surgery and radiation for local management of soft-tissue sarcoma remains controversial on the… CONTINUE READING