Opportunities for Early Detection of Endometrial Cancer in Women With Postmenopausal Bleeding.

  title={Opportunities for Early Detection of Endometrial Cancer in Women With Postmenopausal Bleeding.},
  author={Kristen A. Matteson and Katina Robison and Vanessa L. Jacoby},
  journal={JAMA internal medicine},
  volume={178 9},
Construction of a miRNA-Based Nomogram Model to Predict the Prognosis of Endometrial Cancer
This study found that 12 significantly differentially expressed miRNAs might promote the proliferation, invasion, and metastasis of cancer cells by regulating the expression of upstream target genes, thereby affecting the prognosis of patients with endometrial cancer.
Correlation of Endometrial Thickness and Histopathological in Women with Post-Menopausal Bleeding
TVS evaluation of ET and uterine size is a reliable method of screening postmenopausal women with PMP and no abnormal endometrium detected in post menopause women with endometrial thickness less than 4mm and all causes ofendometrial carceinoma have endometrian thickness more than 9mm.
Immune and Metabolic Dysregulated Coding and Non-coding RNAs Reveal Survival Association in Uterine Corpus Endometrial Carcinoma
An integrated, dysregulated, and scale-free biological network consisting of differentially expressed lnc RNAs, miRNAs, and mRNAs was constructed and revealed two clinic-related modules that showed a close correlation with metabolic and immune functions.
Performance of automatic machine learning versus radiologists in the evaluation of endometrium on computed tomography
It is demonstrated that automatic machine learning can distinguish EC from normal endometrium on routine CT imaging with higher accuracy and specificity than radiologists.
Identi cation of Candidate Biomarkers Associated With the Diagnosis and Prognosis of Endometrial Cancer A Bioinformatics Analysis Identi es
The first A liated Hospital of Guangxi Medical University and the first hospital in China to be liated to Southern Medical University are presented.
Identification of candidate biomarkers associated with the diagnosis and prognosis of endometrial cancer: a bioinformatics analysis
MTHFD2, KIF4A, TPX2, RPS6KA6, and SIX1 were identified as candidate biomarkers for further basic and clinical research on endometrial cancer.
Molecular Oncology of Gynecologic Tumors.
Systematic Analysis of the Clinical Relevance of Cell Division Cycle Associated Family in Endometrial Carcinoma
This study provides new insight into the onset and progression of EC and proposes NUF2 and CDCA2/3/4/5/8 could act as oncogenes and have shown great diagnostic and prognostic promise in improving EC patient detection and survival prediction with accuracy.


Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis
Early detection strategies focused on women with postmenopausal bleeding have the potential to capture as many as 90% of endometrial cancers; however, most women with PMB will not be diagnosed with endometricrial cancer.
ACOG Committee Opinion No. 734: The Role of Transvaginal Ultrasonography in Evaluating the Endometrium of Women With Postmenopausal Bleeding.
  • Medicine
    Obstetrics and gynecology
  • 2018
Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities, and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding.
Endometrial Thickness Measurement for Detecting Endometrial Cancer in Women With Postmenopausal Bleeding: A Systematic Review and Meta-Analysis
Previous meta-analyses on endometrial thickness measurement probably have overestimated its diagnostic accuracy in the detection of endometrian carcinoma, and advise the use of cutoff level of 3 mm for exclusion ofendometrial carcinoma in women with postmenopausal bleeding.
The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review.
It is suggested that investigation of rectal bleeding or anaemia in primary care patients is warranted, irrespective of whether other symptoms are present, and the risks from other single symptoms are lower, though multiple symptoms also warrant investigation.
Evaluation of Abnormal Mammography Results and Palpable Breast Abnormalities
The literature on the evaluation of an abnormal screening mammography result and palpable breast abnormality is reviewed and an evidence-based approach is presented with which to evaluate these two common problems.