Opportunities for Early Detection of Endometrial Cancer in Women With Postmenopausal Bleeding.

@article{Matteson2018OpportunitiesFE,
  title={Opportunities for Early Detection of Endometrial Cancer in Women With Postmenopausal Bleeding.},
  author={Kristen A. Matteson and Katina Robison and Vanessa L. Jacoby},
  journal={JAMA internal medicine},
  year={2018},
  volume={178 9},
  pages={
          1222-1223
        }
}
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References

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Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis
TLDR
Early detection strategies focused on women with postmenopausal bleeding have the potential to capture as many as 90% of endometrial cancers; however, most women with PMB will not be diagnosed with endometricrial cancer.
ACOG Committee Opinion No. 734: The Role of Transvaginal Ultrasonography in Evaluating the Endometrium of Women With Postmenopausal Bleeding.
  • Medicine
    Obstetrics and gynecology
  • 2018
TLDR
Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities, and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding.
Endometrial Thickness Measurement for Detecting Endometrial Cancer in Women With Postmenopausal Bleeding: A Systematic Review and Meta-Analysis
TLDR
Previous meta-analyses on endometrial thickness measurement probably have overestimated its diagnostic accuracy in the detection of endometrian carcinoma, and advise the use of cutoff level of 3 mm for exclusion ofendometrial carcinoma in women with postmenopausal bleeding.
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It is suggested that investigation of rectal bleeding or anaemia in primary care patients is warranted, irrespective of whether other symptoms are present, and the risks from other single symptoms are lower, though multiple symptoms also warrant investigation.
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The literature on the evaluation of an abnormal screening mammography result and palpable breast abnormality is reviewed and an evidence-based approach is presented with which to evaluate these two common problems.