Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry.

  title={Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry.},
  author={Mohammad M Gomari and N. Saraygord-Afshari and Marziye Farsimadan and Neda Rostami and Shahin Aghamiri and Mohammad Morad Farajollahi},
  journal={Biotechnology advances},
Tag-assisted protein purification is a method of choice for both academic researches and large-scale industrial demands. Application of the purification tags in the protein production process can help to save time and cost, but the design and application of tagged fusion proteins are challenging. An appropriate tagging strategy must provide sufficient expression yield and high purity for the final protein products while preserving their native structure and function. Thanks to the recent… Expand
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