Opportunities and challenges for the baculovirus expression system

@article{Oers2011OpportunitiesAC,
  title={Opportunities and challenges for the baculovirus expression system},
  author={Monique M. van Oers},
  journal={Journal of Invertebrate Pathology},
  year={2011},
  volume={107}
}
In this review background information on the baculovirus-insect cell expression system and its applications for producing protein subunits and virus-like particles for vaccine and other purposes is provided. This review will illustrate the principle structure of baculovirus vectors commonly used for heterologous gene expression in insect cells and describe adaptations that have been made over the last 10 years to improve the system in terms of quality of the protein produced and stability of… CONTINUE READING

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