Opportunities and challenges for mesenchymal stem cell-mediated heart repair.

  title={Opportunities and challenges for mesenchymal stem cell-mediated heart repair.},
  author={Douwe Ekke Atsma and Willem E. Fibbe and Ton J Rabelink},
  journal={Current opinion in lipidology},
  volume={18 6},
PURPOSE OF REVIEW Mesenchymal stem cells (or multipotent stromal cells) are emerging as a potent cell type for cardiac cell therapy. This review describes the potential of cardiac mesenchymal stem cell therapy, but also highlights some recently discovered less favorable mesenchymal stem cell characteristics. RECENT FINDINGS Mesenchymal stem cells exert a beneficial effect on cardiac function upon administration to the ischemic myocardium. The mode of action does not seem to involve… CONTINUE READING

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