Opportunistic infection-associated immune reconstitution syndrome in transplant recipients.

  title={Opportunistic infection-associated immune reconstitution syndrome in transplant recipients.},
  author={H Sun and N Heramani Singh},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={53 2},
Reversal of pathogen-induced immunosuppression upon employment of effective antimicrobial therapy and withdrawal of iatrogenic immunosuppression has the potential to shift the host immune repertoire towards pathologic inflammatory responses conducive to immune reconstitution syndrome (IRS). Posttransplant IRS has been observed with fungi, M. tuberculosis, cytomegalovirus, and polyoma virus nephropathy. This review discusses the existing state of knowledge regarding IRS and the immune mechanisms… CONTINUE READING

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Transplant infectious disease : an official journal of the Transplantation Society • 2011

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