Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus.

@article{Kuo1998OplAZ,
  title={Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus.},
  author={Jeanne Kuo and Mukund Patel and Joshua T. Gamse and Christa S Merzdorf and Xing Liu and V. S. Apekin and Hazel L. Sive},
  journal={Development},
  year={1998},
  volume={125 15},
  pages={2867-82}
}
In order to study the mechanism of neural patterning in Xenopus, we used subtractive cloning to isolate genes activated early during this process. One gene isolated was opl, (odd-paired-like) that resembles the Drosophila pair-rule gene odd-paired and encodes a zinc finger protein that is a member of the Zic gene family. At the onset of gastrulation, opl is expressed throughout the presumptive neural plate, indicating that neural determination has begun at this stage while, by neurula, opl… CONTINUE READING
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